氏名

カワカミ リョウコ

川上 諒子

職名

講師(任期付) (https://researchmap.jp/7000012065)

所属

(スポーツ科学部)

連絡先

URL等

研究者番号
50617818
ORCID ID
0000-0001-8211-1553

学歴・学位

学歴

2003年04月-2006年03月 鹿屋体育大学 体育学部 体育学
2006年04月-2008年03月 鹿屋体育大学大学院 体育学研究科 体育学
2012年04月-2015年03月 早稲田大学大学院 スポーツ科学研究科 スポーツ科学

学位

博士(スポーツ科学) 課程 早稲田大学 スポーツ科学

経歴

2008年04月-2013年03月国立健康・栄養研究所 健康増進研究部 技術補助員
2012年04月-2013年03月東京ガス株式会社 安全健康・福利室 準職員(業務委託)
2013年04月-2015年03月国立健康・栄養研究所 健康増進研究部 流動研究員
2013年04月-2015年03月日本学術振興会 特別研究員(DC2)
2015年04月-国立健康・栄養研究所 健康増進研究部 協力研究員
2015年04月-2018年03月早稲田大学スポーツ科学学術院 助手
2017年04月-2019年03月国立国際医療研究センター疫学予防研究部客員研究員
2018年04月-早稲田大学スポーツ科学学術院 講師(任期付)
2018年12月-新潟大学大学院医歯学総合研究科客員研究員

所属学協会

日本体力医学会

日本体育学会

日本疫学会

日本公衆衛生学会

アメリカスポーツ医学会(ACSM; American College of Sports Medicine)

日本運動疫学会

日本体育測定評価学会

日本健康支援学会

委員歴・役員歴(学外)

2015年09月-日本体力医学会評議員
2015年09月-日本運動疫学会セミナー委員
2017年10月-日本運動疫学会総務委員
2020年04月-日本健康支援学会評議員
2020年04月-日本健康支援学会編集委員

受賞

鹿屋体育大学 学業成績優秀者学長表彰 (3年次早期卒業)

2006年03月授与機関:鹿屋体育大学

第64回日本体育学会 若手研究奨励賞

2013年08月授与機関:第64回日本体育学会

61st American College of Sports Medicine Annual Meeting International Student Award

2014年05月授与機関:アメリカスポーツ医学会(ACSM; American College of Sports Medicine)

第6回日本介護予防・健康づくり学会大会 若手奨励賞

2018年11月授与機関:第6回日本介護予防・健康づくり学会

研究分野

キーワード

身体活動、運動、体力、全身持久力、筋力、サルコペニア、2型糖尿病、メタボリックシンドローム、評価法、コホート研究、疫学、公衆衛生学、スポーツ観戦

科研費分類

複合領域 / 健康・スポーツ科学 / 応用健康科学

論文

A prospective cohort study of muscular and performance fitness and risk of hearing loss: the Niigata Wellness Study

Kawakami R, Sawada SS, Kato K, Gando Y, Momma H, Oike H, Miyachi M, Lee IM, Blair SN, Tashiro M, Horikawa C, Matsubayashi Y, Yamada T, Fujihara K, Sone H

Am J Med査読有りin press

PubMedDOI

Physical fitness and dyslipidemia among Japanese: a cohort study from the Niigata Wellness Study

Momma H, Kato K, Sawada SS, Gando Y, Kawakami R, Miyachi M, Nagatomi R, Tashiro M, Matsubayashi Y, Kodama S, Iwanaga M, Fujihara K, Sone H

J Epidemiol査読有りin press

PubMedDOI

Simple-measured leg muscle strength and the prevalence of diabetes among Japanese males: A cross-sectional analysis of data from the Kameda Health Study

Miyamoto R, Sawada SS, Gando Y, Matsushita M, Kawakami R, Muranaga S, Osawa Y, Ishii K, Oka K

J Phys Ther Sci査読有り32(1)p.1 - 62020年01月-

PubMedDOI

Micronutrient intake adequacy in men and women with a healthy Japanese dietary pattern

Ito T, Tanisawa K, Kawakami R, Usui C, Ishii K, Suzuki K, Sakamoto S, Muraoka I, Oka K, Higuchi M

Nutrients査読有り12(1)p.E62019年12月-

PubMedDOI

Effect of watching professional baseball at a stadium on health-related outcomes among Japanese older adults: A randomized controlled trial

Kawakami R, Sawada SS, Ito T, Gando Y, Fukushi T, Yoshino A, Kurita S, Oka K, Sakamoto S, Higuchi M

Geriatr Gerontol Int査読有り19(8)p.717 - 7222019年08月-

PubMedDOI

Accuracy of 12 Wearable Devices for Estimating Physical Activity Energy Expenditure Using a Metabolic Chamber and the Doubly Labeled Water Method: Validation Study

Murakami H#, Kawakami R#, Nakae S, Yamada Y, Nakata Y, Ohkawara K, Sasai H, Ishikawa-Takata K, Tanaka S, Miyachi M

JMIR Mhealth Uhealth査読有り7(8)p.e139382019年08月-

PubMedDOI

Leisure-time physical activity and DNA damage among Japanese workers

Kawakami R, Kashino I, Kasai H, Kawai K, Li YS, Nanri A, Higuchi M, Mizoue T

PloS One査読有り14(2)p.e02124992019年02月-

PubMedDOI

Stand-up test overestimates the decline of locomotor function in taller people: a cross-sectional analysis of data from the Kamada Health Study

Miyamoto R, Sawada SS, Gando Y, Matsushita M, Kawakami R, Muranaga S, Osawa Y, Ishii K, Oka K

J Phys Ther Sci査読有り31(2)p.175 - 1842019年02月-

PubMedDOI

Combined aerobic and resistance training and incidence of diabetes: A retrospective cohort study in Japanese older women

Sawada SS, Gando Y, Kawakami R, Blair SN, Lee IM, Tamura Y, Tsuda H, Saito H, Miyachi M

J Diabetes Investig査読有り10(4)p.997 - 10032019年07月-

PubMedDOI

Frequency of achieving a 'fit' cardiorespiratory fitness level and hypertension: a cohort study

Momma H, Sawada SS, Sloan RA, Gando Y, Kawakami R, Miyachi M, Fukunaka Y, Okamoto T, Tsukamoto K, Nagatomi R, Blair SN

J Hypertens査読有り37(4)p.820 - 8262019年04月-

PubMedDOI

Physical fitness tests and type 2 diabetes among Japanese: a longitudinal study from the Niigata Wellness Study

Momma H, Sawada SS, Kato K, Gando Y, Kawakami R, Miyachi M, Huang C, Nagatomi R, Tashiro M, Ishizawa M, Kodama S, Iwanaga M, Fujihara K, Sone H

J Epidemiol査読有り29(4)p.139 - 1462019年04月-

PubMedDOI

Dietary patterns and abdominal obesity in middle-aged and elderly Japanese adults: The WASEDA'S Health Study

Ito T, Kawakami R, Tanisawa K, Miyawaki R, Ishii K, Torii S, Suzuki K, Sakamoto S, Muraoka I, Oka K, Higuchi M, WASEDA'S Health Study Group

Nutrition査読有り58p.149 - 1552019年-

PubMedDOI

Relationship between cardiorespiratory fitness and non-high-density lipoprotein cholesterol: a cohort study

Watanabe N, Sawada SS, Shimada K, Lee IM, Gando Y, Momma H, Kawakami R, Miyachi M, Hagi Y, Kinugawa C, Okamoto T, Tsukamoto K, Blair SN

J Atheroscler Thromb査読有り25(12)p.1196 - 12052018年12月-

PubMedDOI

Combined association of cardiorespiratory fitness and family history of hypertension on the incidence of hypertension: a long-term cohort study of Japanese males

Gando Y, Sawada SS, Kawakami R, Momma H, Shimada K, Fukunaka Y, Okamoto T, Tsukamoto K, Miyachi M, Lee IM, Blair SN

Hypertens Res査読有り41(12)p.1063 - 10692018年12月-

PubMedDOI

Simultaneous validation of seven physical activity questionnaires used in Japanese cohorts for estimating energy expenditure: A doubly labeled water study

Sasai H, Nakata Y, Murakami H, Kawakami R, Nakae S, Tanaka S, Ishikawa-Takata K, Yamada Y, Miyachi M

J Epidemiol査読有り28(10)p.437 - 4422018年10月-

PubMedDOI

Caffeine consumption is associated with higher level of physical activity in Japanese women

Tripette J, Murakami H, Hara H, Kawakami R, Gando Y, Ohno H, Miyatake N, Miyachi M

Int J Sport Nutr Exerc Metab査読有り28(5)p.474 - 4792018年09月-

PubMedDOI

高齢者のプロ野球観戦頻度と身体的・社会的・心理的特徴

澤田亨, 川上諒子, 伊藤智子, 丸藤祐子, 福士朝尋, 藤江亮介, 岡浩一朗, 坂本静男, 樋口満

生涯スポーツ学研究査読有り14(2)p.15 - 262018年08月-

DOI

Objectively measured physical activity and low back pain in Japanese men

Hashimoto Y, Matsudaira K, Sawada SS, Gando Y, Kawakami R, Kinugawa C, Okamoto T, Tsukamoto K, Miyachi M, Naito H, Blair SN

J Phys Act Health査読有り15(6)p.417 - 4222018年06月-

PubMedDOI

Long-term impact of cardiorespiratory fitness on type 2 diabetes incidence: A cohort study of Japanese men

Kawakami R, Sawada SS, Lee IM, Gando Y, Momma H, Terada S, Kinugawa C, Okamoto T, Tsukamoto K, Higuchi M, Miyachi M, Blair SN

J Epidemiol査読有り28(5)p.266 - 2732018年05月-

PubMedDOI

Importance of achieving a “fit” cardiorespiratory fitness level for several years on the incidence of type 2 diabetes mellitus: a Japanese cohort study

Momma H, Sawada SS, Sloan RA, Gando Y, Kawakami R, Terada S, Miyachi M, Kinugawa C, Okamoto T, Tsukamoto K, Huang C, Nagatomi R, Blair SN

J Epidemiol査読有り28(5)p.230 - 2362018年05月-

PubMedDOI

Daily Step Count and All-Cause Mortality in a Sample of Japanese Elderly People: A Cohort Study

Yamamoto N, Miyazaki H, Shimada M, Nakagawa N, Sawada SS, Nishimuta M, Kimura Y, Kawakami R, Nagayama H, Asai H, Lee IM, Blair SN, Yoshitake Y

BMC Public Health査読有り18(1)p.5402018年04月-

PubMedDOI

Association between objectively measured physical activity and body mass index with low back pain: a large-scale cross-sectional study of Japanese men

Hashimoto Y, Matsudaira K, Sawada SS, Gando Y, Kawakami R, Sloan RA, Kinugawa C, Okamoto T, Tsukamoto K, Miyachi M, Naito H

BMC Public Health査読有り18(1)p.3412018年03月-

PubMedDOI

The association of fit-fat index with incident diabetes in Japanese men: A prospective cohort study

Sloan RA, Sawada SS, Lee IM, Gando Y, Kawakami R, Okamoto T, Tsukamoto K, Miyachi M

Sci Rep査読有り8(1)p.5692018年01月-

PubMedDOI

Tracking of cardiorespiratory fitness in Japanese men

Yamamoto N, Sawada SS, Lee IM, Gando Y, Kawakami R, Murakami H, Miyachi M, Yoshitake Y, Asai H, Okamoto T, Tsukamoto K, Tanaka H, Blair SN

J Phys Fitness Sports Med査読有り7(1)p.25 - 332018年01月-

DOI

Consistently high level of cardiorespiratory fitness and incidence of type 2 diabetes

Momma, Haruki; Momma, Haruki; Sawada, Susumu S.; Lee, I. Min; Lee, I. Min; Gando, Yuko; Kawakami, Ryoko; Terada, Shin; Miyachi, Motohiko; Kinugawa, Chihiro; Okamoto, Takashi; Tsukamoto, Koji; Huang, Cong; Nagatomi, Ryoichi; Blair, Steven N.

Med Sci Sports Exerc査読有り49(10)p.2048 - 20552017年10月-

PubMedDOIScopus

詳細

ISSN:01959131

概要:© Copyright 2017 by the American College of Sports Medicine. Purpose Although the benefit of high cardiorespiratory fitness (CRF) for the prevention of type 2 diabetes mellitus (T2DM) is widely accepted, whether consistently high CRF is necessary or transiently high CRF is sufficient is unclear. The present study was conducted to examine the hypothesis that consistently high level of CRF is more beneficial than transiently high CRF for the prevention of T2DM. Methods This cohort study was conducted in nondiabetic 7158 men age 20 to 60 yr, enrolled from 1986 to 1987. The area under the curve with respect to ground (AUC G ) for CRF measurements during an 8-yr measurement period (1979-1987) was calculated as an index of integrated CRF level during the period. The differences (ΔAUC P ) between AUC G and peak AUC (peak CRF-measurement period) was also calculated as an index of the presence and the size of a "spike" in CRF. T2DM was defined by fasting blood glucose and a self-reported diagnosis of diabetes for participants with blood tests. For participants without blood tests, T2DM was defined by the result of oral glucose test after a nonfasting urinary test and a self-reported diagnosis of diabetes. T2DM was determined on health checkups until 2009. Results During the follow-up period, 1495 men developed T2DM. After adjustment for confounders, as compared with the first quartile of AUC G for CRF, the hazard ratio (95% confidence interval) for the second, third, and fourth quartiles were 0.87 (0.76 to 1.00), 0.80 (0.68 to 0.95), and 0.72 (0.58 to 0.89), respectively. For CRF spike, there was no association between ΔAUC P in CRF and the incidence of T2DM. Conclusions Consistently higher level of CRF over time was associated with lower risk of T2DM.

国内のコホート研究で使用されている身体活動質問票による総エネルギー消費量の算出に向けたスコアリングプロトコル

中田由夫, 笹井浩行, 村上晴香, 川上諒子, 田中茂穂, 宮地元彦

運動疫学研究査読有り19(2)p.83 - 922017年09月-

Development of prediction equations for estimating appendicular skeletal muscle mass in Japanese men and women

Furushima, Taishi; Miyachi, Motohiko; Iemitsu, Motoyuki; Murakami, Haruka; Kawano, Hiroshi; Gando, Yuko; Kawakami, Ryoko; Sanada, Kiyoshi

Journal of physiological anthropology査読有り36(1)p.342017年08月-

PubMedDOIScopus

詳細

概要:BACKGROUND: This study aimed to develop and cross-validate prediction equations for estimating appendicular skeletal muscle mass (ASM) and to examine the relationship between sarcopenia defined by the prediction equations and risk factors for cardiovascular diseases (CVD) or osteoporosis in Japanese men and women. METHODS: Subjects were healthy men and women aged 20-90 years, who were randomly allocated to the following two groups: the development group (D group; 257 men, 913 women) and the cross-validation group (V group; 119 men, 112 women). To develop prediction equations, stepwise multiple regression analyses were performed on data obtained from the D group, using ASM measured by dual-energy X-ray absorptiometry (DXA) as a dependent variable and five easily obtainable measures (age, height, weight, waist circumference, and handgrip strength) as independent variables. RESULTS: When the prediction equations for ASM estimation were applied to the V group, a significant correlation was found between DXA-measured ASM and predicted ASM in both men and women (R 2 = 0.81 and R 2 = 0.72). Our prediction equations had higher R 2 values compared to previously developed equations (R 2 = 0.75-0.59 and R 2 = 0.69-0.40) in both men and women. Moreover, sarcopenia defined by predicted ASM was related to risk factors for osteoporosis and CVD, as well as sarcopenia defined by DXA-measured ASM. CONCLUSIONS: In this study, novel prediction equations were developed and cross-validated in Japanese men and women. Our analyses validated the clinical significance of these prediction equations and showed that previously reported equations were not applicable in a Japanese population.

Influence of watching professional baseball on Japanese elders’ affect and subjective happiness

Kawakami R, Sawada SS, Ito T, Gando Y, Fukushi T, Fujie R, Oka K, Sakamoto S, Higuchi M

Gerontol Geriatr Med査読有り3p.1 - 62017年-

PubMedDOI

Greater progression of age-related aortic stiffening in adults with poor trunk flexibility: A 5-year longitudinal study

Gando Y, Murakami H, Yamamoto K, Kawakami R, Ohno H, Sawada SS, Miyatake N, Miyachi M

Front Physiol.査読有り8p.454

PubMedDOI

Obesity and low back pain: A retrospective cohort study of Japanese males

Hashimoto Y, Matsudaira K, Sawada SS, Gando Y, Kawakami R, Kinugawa C, Okamoto T, Tsukamoto K, Miyachi M, Naito H

J Phys Ther Sci査読有り29(6)p.978 - 9832017年-

PubMedDOI

A pilot lifestyle intervention study: effects of an intervention using an activity monitor and Twitter on physical activity and body composition

Nishiwaki M, Nakashima N, Ikegami Y, Kawakami R, Kurobe K, Matsumoto N

J Sports Med Phys Fitness査読有り57(4)p.402 - 4102017年04月-

PubMedDOIScopus

詳細

ISSN:00224707

概要:© 2016 EDIZIONI MINERVA MEDICA.BACKGROUND: This pilot study aimed to examine the effects of a lifestyle intervention comprising an activity monitor and the concurrent use of Twitter, on physical activity (PA) and body composition. METHODS: Seventeen healthy volunteers (36±3 years) were randomly assigned to normal (N, N.=8) or Twitter (T, N.=9) intervention groups for six weeks. Participants in both groups wore an activity monitor but those in the T group also tweeted daily about their PA. An observer read the tweets from each participant and provided feedback. Body composition was determined using bioelectrical impedance analysis before and after the intervention. RESULTS: Significantly more daily steps and PA at an intensity of ≥3 metabolic equivalents (METs) were recorded by the T than the N during six weeks. The number of steps and PA did not significantly change over time in the N, but significantly increased in the T from weeks one to six (8170±1130 to 12,934±1400 steps/day and 2.6±0.5 to 5.0±0.8 METsh/day). In addition, significantly more body fat was lost in the T, than in the N (-1.1±0.2 vs. -0.1±0.3 kg), and the changes in PA significantly correlated with the changes in body fat (r=-0.713). CONCLUSIONS: Lifestyle intervention can increase daily PA and reduce body fat more effectively when using an activity monitor and Twitter than an activity monitor alone.

Visceral fat area is a strong predictor of leukocyte cell-derived chemotaxin 2, a potential biomarker of dyslipidemia

Tanisawa K, Taniguchi H, Sun X, Ito T, Kawakami R, Sakamoto S, Higuchi M

PloS One査読有り12(3)p.e01733102017年03月-

PubMedDOIScopus

詳細

概要:© 2017 Tanisawa et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.Background Leukocyte cell-derived chemotaxin 2 (LECT2) is a hepatokine linking obesity to skeletal muscle insulin resistance. Although previous studies reported that obesity was associated with high levels of circulating LECT2 in human, the associations of detailed body fat distribution with LECT2 levels have not been examined. Furthermore, although animal study suggested that exercise decreased circulating LECT2 levels, it remains unknown whether physical fitness is associated with LECT2 levels in human. We therefore examined the relationship of plasma LECT2 levels with various adiposity indices and cardiorespiratory fitness (CRF) in middle-aged and elderly Japanese men. Furthermore, we examined the relationship of LECT2 levels with the presence of metabolic syndrome, hypertension, insulin resistance and dyslipidemia to determine the clinical significance of measuring circulating LECT2. Materials and methods This was a cross-sectional study of 143 Japanese men (age: 30-79 years). Participants' plasma LECT2 levels were measured by an enzyme-linked immunosorbent assay. To assess their abdominal fat distributions, visceral fat area (VFA) and subcutaneous fat area (SFA) were measured using magnetic resonance imaging. CRF was assessed by measuring peak oxygen uptake (VO2peak). Results All adiposity indices measured in this study were positively correlated with plasma LECT2 levels, while VO2peak was negatively correlated with LECT2 levels after adjustment for age. The correlations, except for VFA were no longer significant with further adjustment for VFA. Stepwise multiple linear regression analysis revealed that VFA was the strongest predictor of plasma LECT2 levels. Plasma LECT2 levels differed based on the presence of metabolic syndrome and dyslipidemia, but not hypertension and insulin resistance. Logistic regression analyses revealed that plasma LECT2 levels were significantly associated with dyslipidemia independently of VFA; VFA was not significantly associated with dyslipidemia after adjustment for LECT2. Conclusion VFA was the strongest predictor of plasma LECT2 that is a potential biomarker linking visceral obesity to dyslipidemia.

Comparison between clinical significance of height-adjusted and weight-adjusted appendicular skeletal muscle mass

Furushima, Taishi; Miyachi, Motohiko; Iemitsu, Motoyuki; Murakami, Haruka; Kawano, Hiroshi; Gando, Yuko; Kawakami, Ryoko; Sanada, Kiyoshi

J Physiol Anthropol査読有り36(1)p.152017年02月-

PubMedDOIScopus

詳細

概要:BACKGROUND: This study aimed to compare relationships between height- or weight-adjusted appendicular skeletal muscle mass (ASM/Ht2 or ASM/Wt) and risk factors for cardiometabolic diseases or osteoporosis in Japanese men and women. METHODS: Subjects were healthy Japanese men (n = 583) and women (n = 1218). The study population included a young group (310 men and 357 women; age, 18-40 years) and a middle-aged and elderly group (273 men and 861 women; age, ≥41 years). ASM was measured by dual-energy X-ray absorptiometry. The reference values for class 1 and 2 sarcopenia in each sex were defined as values one and two standard deviations below the sex-specific means of the young group, respectively. RESULTS: The reference values for class 1 and 2 sarcopenia defined by ASM/Ht2 were 7.77 and 6.89 kg/m2 in men and 6.06 and 5.31 kg/m2 in women, respectively. The reference values for ASM/Wt were 35.0 and 32.0% in men and 29.6 and 26.4% in women, respectively. In both men and women, ASM/Wt was negatively correlated with higher triglycerides (TG) and positively correlated with serum high-density lipoprotein cholesterol (HDL-C), but these associations were not found in height-adjusted ASM. In women, TG, systolic blood pressure, and diastolic blood pressure in sarcopenia defined by ASM/Wt were significantly higher than those in normal subjects, but these associations were not found in sarcopenia defined by ASM/Ht2. Whole-body and regional bone mineral density in sarcopenia defined by ASM/Ht2 were significantly lower than those in normal subjects, but these associations were not found in sarcopenia defined by ASM/Wt. CONCLUSIONS: Weight-adjusted definition was able to identify cardiometabolic risk factors such as TG and HDL-C while height-adjusted definition could identify factors for osteoporosis.

中高年を対象とした食事調査票からの食事パターンの抽出と栄養素摂取量の評価

伊藤 智子;谷澤 薫平;川上 諒子;樋口 満

日本公衆衛生雑誌査読有り63(11)p.653 - 6632016年-

PubMedDOICiNii

詳細

概要:

目的 食事と健康との関連において食事パターンを用いた検討が行われているが,食事パターンを構成する複数の栄養素について,適正な量が摂取されているかを検討した報告は少ない。そこで,本研究では,主成分分析により中高年男性における代表的な食事パターンを同定し,各食事パターンと栄養素摂取量との関連を検討した。さらに,微量栄養素について,食事摂取基準(2010年版)で推奨されている指標を用いて複数の微量栄養素が適正量に摂取されているかを数値化して簡易的に評価し,食事パターンとの関連を検討することを目的とした。

方法 40歳から79歳の中高年男性229人を対象として,簡易型自記式食事歴法質問票 brief-type self-administered diet history questionnaire(BDHQ)による栄養調査を行った。52の食品および飲料の摂取量から主成分分析を行い,食事パターンを同定した。BDHQ によって推定された微量栄養素のうち,食事摂取基準値が策定されている21種類の微量栄養素が適正量に摂取されているかを数値化して評価するために Dietary reference intakes score(DRIs-score)を作成した。各食事パターンにおいて複数の微量栄養素が適正量摂取されているかを検討するために,各食事パターンの主成分得点と DRIs-score において Spearman の順位相関係数を求めた。

結果 主成分分析の結果,3 つの食事パターンが同定された。第 1 食事パターンは野菜,果物,海草,きのこ,いも類が多く,ご飯(めし)が少ない「副菜型」,第 2 食事パターンはアルコールが多い「晩酌型」,第 3 食事パターンは果物・乳製品・菓子類が多い「間食型」とした。第 1 食事パターンの「副菜型」において,主成分得点と DRIs-score を構成するすべての微量栄養素との間に有意な相関関係が認められ,DRIs-score との間には有意な正の相関関係(ρ=0.782, P<0.001)が認められた。

結論 第 1 食事パターンの「副菜型」の主成分得点は,日本人の食事摂取基準をもとに複数の微量栄養素の摂取が適正量であるかを評価した DRIs-score と相関し,第 1 食事パターンの重み付けが高い程,微量栄養素の栄養バランスが良好であることが示唆された。

The effects of exercise training under mild hypoxic conditions on body composition and circulating adiponectin in postmenopausal women

Nishiwaki M, Kawakami R, Saito K, Tamaki H, Ogita F

Clin Physiol Funct Imaging査読有り36(6)p.468 - 4752016年-

PubMedDOI

Weight change after 20 years of age and the incidence of dyslipidemia: A cohort study of Japanese male workers

Sogabe, N.; Sawada, S. S.; Lee, I. M.; Lee, I. M.; Kawakami, R.; Kawakami, R.; Ishikawa-Takata, K.; Nakata, Y.; Mitomi, M.; Noguchi, J.; Tsukamoto, K.; Miyachi, M.; Blair, S. N.; Blair, S. N.

Journal of Public Health (United Kingdom)査読有り38(2)p.e77 - e832016年01月-

PubMedDOIScopus

詳細

ISSN:17413842

概要:Background While heavier weight is known to increase the incidence of dyslipidemia, limited data are available on the relationship between weight gain and its development. Methods A total of 2647 males were categorized into the following four groups according to the difference between their self-reported weight at 20 years of age and their measured weight in 1994-95: a loss of 5% (decrease), loss of ,5% or gain of ,5% (no change), gain of 5 to ,15% (increase) and gain of 15% (sizable increase). They were followed up until their 2002-03 health examination. Using the 'no change' group as reference, the multivariable-adjusted odds ratio (adjusted for age, body mass index at 20 years of age, physical activity, smoking and alcohol intake) and 95% confidence interval (95% CI) for the incidence of dyslipidemia were determined using logistic regression models. Results A total of 1342 participants developed dyslipidemia during the follow-up period. The 'increase' and 'sizable increase' groups had odds ratios for the incidence of dyslipidemia of 1.97 (95% CI, 1.59-2.45) and 2.68 (2.15-3.34), respectively, demonstrating that there was a significant dose-response association between weight gain since 20 years of age and the incidence of dyslipidemia (P, 0.001 for trend). Conclusion These results suggest that dyslipidemia could be prevented by avoiding weight gain in adulthood.

Accuracy of wearable devices for estimating total energy expenditure: Comparisonwith metabolic chamber and doubly labeledwater method

Murakami, Haruka; Kawakami, Ryoko; Nakae, Satoshi; Nakata, Yoshio; Ishikawa-Takata, Kazuko; Tanaka, Shigeho; Miyachi, Motohiko

JAMA Internal Medicine査読有り176(5)p.702 - 7032016年05月-

PubMedDOIScopus

詳細

ISSN:21686106

Cardiorespiratory Fitness Suppresses Age-Related Arterial Stiffening in Healthy Adults: A 2-Year Longitudinal Observational Study

Gando, Yuko; Murakami, Haruka; Kawakami, Ryoko; Kawakami, Ryoko; Yamamoto, Kenta; Yamamoto, Kenta; Kawano, Hiroshi; Kawano, Hiroshi; Tanaka, Noriko; Tanaka, Noriko; Sawada, Susumu S.; Miyatake, Nobuyuki; Miyachi, Motohiko

Journal of Clinical Hypertension査読有り18(4)p.292 - 2982016年04月-

PubMedDOIScopus

詳細

ISSN:15246175

概要:© 2016 Wiley Periodicals, Inc. Cardiorespiratory fitness is negatively associated with arterial stiffness, although it is unclear whether it is associated with prospective arterial stiffness changes. The authors examined cardiorespiratory fitness and arterial stiffness progression in a 2-year follow-up study of 470 healthy men and women aged 26 to 69 years. Peak oxygen uptake (V˙O2peak) was measured at baseline using a graded cycle exercise test. Arterial stiffness was assessed using brachial-ankle pulse wave velocity (baPWV) at baseline and after 2 years. Two-year changes in baPWV were significantly higher in patients in the lowest V˙O2peak tertile (28.8±7.6 cm/s) compared with those in the highest V˙O2peak tertile (-1.4±7.5 cm/s) (P=024) and were inversely correlated with V˙O2peak (r=-112, P=015). Stepwise multiple regression analysis revealed that age, glucose, baPWV, V˙O2peak, and sex were independent correlates of 2-year changes in baPWV, suggesting that higher cardiorespiratory fitness is associated with age-related arterial stiffening suppression.

Body mass index and kidney stones: A cohort study of Japanese men

Yoshimura, Eiichi; Yoshimura, Eiichi; Sawada, Susumu S.; Lee, I. Min; Lee, I. Min; Gando, Yuko; Kamada, Masamitsu; Kamada, Masamitsu; Matsushita, Munehiro; Matsushita, Munehiro; Kawakami, Ryoko; Kawakami, Ryoko; Ando, Ryosuke; Okamoto, Takashi; Tsukamoto, Koji; Miyachi, Motohiko; Blair, Steven N.; Blair, Steven N.

Journal of Epidemiology査読有り26(3)p.131 - 1362016年01月-

PubMedDOIScopus

詳細

ISSN:09175040

概要:© 2015 Eiichi Yoshimura et al. Background: In Japan, the incidence of kidney stones has increased markedly in recent decades. Major causes of kidney stones remain unclear, and limited data are available on the relationship between overweight/obesity and the incidence of kidney stones. We therefore evaluated body mass index (BMI) and the incidence of kidney stones in Japanese men. Methods: Of the workers at a gas company, 5984 males aged 20-40 years underwent a medical examination in 1985 (baseline). This study includes 4074 of the men, who were free of kidney stones at baseline and underwent a second medical examination performed between April 2004 and March 2005. BMI was calculated from measured height and weight in 1985, and men were categorized into tertiles. The development of kidney stones during followup was based on self-reports from questionnaires at the second medical examination. Results: The average duration of follow-up was 19 years, with 258 participants developing kidney stones during this period. Using the lowest BMI (1st tertile) group as a reference, the hazard ratios (95% confidence intervals [CIs]) for the 2nd and 3rd BMI tertiles were: 1.26 (95% CI, 0.92-1.73) and 1.44 (95% CI, 1.06-1.96), respectively (P for trend = 0.019). After additionally adjusting for potential confounders, such as age, systolic blood pressure, cardiorespiratory fitness, cigarette smoking, and alcohol consumption, the hazard ratios were 1.28 (95% CI, 0.93-1.76) and 1.41 (95% CI, 1.02-1.97), respectively (P for trend = 0.041). Conclusions: These results suggest that increased BMI is a risk factor for kidney stones in Japanese men.

Dynapenic Obesity and Prevalence of Type 2 Diabetes in Middle-Aged Japanese Men

Kawakami Ryoko;Sawada Susumu S.;Lee I-Min;Matsushita Munehiro;Gando Yuko;Okamoto Takashi;Tsukamoto Koji;Higuchi Mitsuru;Miyachi Motohiko;Blair Steven N.

Journal of Epidemiology査読有り25(10)p.656 - 6622015年-

PubMedDOICiNii

詳細

ISSN:0917-5040

概要:Background: The independent and combined associations of muscle strength and obesity on the prevalence of type 2 diabetes in Japanese men remain unclear.
Methods: Hand grip strength was cross-sectionally evaluated between 2011 and 2013 to assess muscle strength in 5039 male workers aged 40 to 64 years. Weight and height were measured, and overweight/obesity was defined as a body mass index ≥25 kg/m2. The prevalence of type 2 diabetes, defined as fasting plasma glucose ≥126 mg/dL and/or hemoglobin A1c ≥6.5% and/or self-reported physician-diagnosed diabetes, was evaluated. Odds ratios (OR) and 95% confidence intervals (95% CI) for the prevalence of type 2 diabetes were obtained using a logistic regression model.
Results: In total, 611 participants had type 2 diabetes, and 1763 participants were overweight/obese. After adjustment for covariates, we found an inverse association between muscle strength and the prevalence of type 2 diabetes (P for trend <0.01). In addition, when the analyses were stratified by obesity status, the multivariable-adjusted OR per 2-standard-deviation increase in muscle strength was 0.64 (95% CI, 0.49–0.83) in the overweight/obese group, compared to a weaker relationship in the normal-weight group (OR 0.79 per 2-standard-deviation increase; 95% CI, 0.60–1.06).
Conclusions: Dynapenia, an age-related decrease in muscle strength, is associated with increased prevalence of type 2 diabetes, and this relationship is stronger in overweight/obese middle-aged Japanese men than in normal-weight men.

Calf circumference as a surrogate marker of muscle mass for diagnosing sarcopenia in Japanese men and women

Kawakami, Ryoko;Murakami, Haruka;Sanada, Kiyoshi;Tanaka, Noriko;Sawada, Susumu S.;Tabata, Izumi;Higuchi, Mitsuru;Miyachi, Motohiko

Geriatr Gerontol Int査読有り15(8)p.969 - 9762015年08月-

PubMedDOIWoS

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ISSN:1444-1586

Cardiorespiratory Fitness is a Strong Predictor of the Cardio-ankle Vascular Index in Hypertensive Middle-aged and Elderly Japanese Men

Tanisawa, Kumpei;Ito, Tomoko;Sun, Xiaomin;Kawakami, Ryoko;Oshima, Satomi;Gando, Yuko;Cao, Zhen-Bo;Sakamoto, Shizuo;Higuchi, Mitsuru

J Atheroscler Thromb査読有り22(4)p.379 - 3892015年-

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ISSN:1340-3478

"Add 10 min for your health": The new Japanese recommendation for physical activity based on dose-response analysis

Murakami H, Tripette J, Kawakami R, Miyachi M

J Am Coll Cardiol査読有り65(11)p.1153 - 11542015年03月-

PubMedDOI

健康づくりのための身体活動基準2013による身体活動評価とメタボリックシンドローム:横断研究

川上諒子, 村上晴香, 宮武伸行, 澤田亨, 樋口満, 宮地元彦

日本公衆衛生雑誌査読有り61(12)p.705 - 7172014年12月-

PubMedDOI

Circulating leptin levels are associated with physical activity or physical fitness in Japanese

Miyatake N, Murakami H, Kawakami R, Tabata I, Miyachi M; The NEXIS Study Group

Environ Health Prev Med査読有り19(5)p.362 - 3662014年09月-

PubMedDOI

Wii Fit U intensity and enjoyment in adults

Tripette J, Murakami H, Ando T, Kawakami R, Tanaka N, Tanaka S, Miyachi M

BMC Res Notes査読有り7p.5672014年08月-

PubMedDOI

Circulating adiponectin levels are associated with peak oxygen uptake in Japanese

Miyatake N, Numata T, Murakami H, Kawakami R, Sanada K, Tabata I, Miyachi M; NEXIS Study Group

Environ Health Prev Med査読有り19(4)p.279 - 2852014年07月-

PubMedDOI

体力の基準値策定のためのエビデンス

澤田亨, 村上晴香, 川上諒子, 宮地元彦

臨床スポーツ医学31(1)p.36 - 412014年01月-

身体活動基準・指針の策定の方針と方法

村上晴香, 川上諒子, 田中憲子, 宮地元彦

臨床スポーツ医学31(1)p.18 - 242014年01月-

Higher cardiorespiratory fitness attenuates the risk of atherosclerosis associated with ADRB3 Trp64Arg polymorphism

Iemitsu, Motoyuki;Fujie, Shumpei;Murakami, Haruka;Sanada, Kiyoshi;Kawano, Hiroshi;Gando, Yuko;Kawakami, Ryoko;Tanaka, Noriko;Miyachi, Motohiko

Eur J Appl Physiol査読有り114(7)p.1421 - 14282014年-

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ISSN:1439-6319

The Q223R polymorphism in the leptin receptor associates with objectively measured light physical activity in free-living Japanese

Murakami, Haruka;Iemitsu, Motoyuki;Fuku, Noriyuki;Sanada, Kiyoshi;Gando, Yuko;Kawakami, Ryoko;Miyachi, Motohiko

Physiol Behav査読有り129p.199 - 2042014年04月-

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詳細

ISSN:0031-9384

Light-intensity physical activity is associated with insulin resistance in elderly Japanese women independent of moderate-to vigorous-intensity physical activity.

Gando Yuko;Murakami Haruka;Kawakami Ryoko;Tanaka Noriko;Sanada Kiyoshi;Tabata Izumi;Higuchi Mitsuru;Miyachi Motohiko

J Phys Act Health査読有り11(2)p.266 - 2712014年02月-

PubMedDOI

詳細

ISSN:1543-5474

概要:BACKGROUND:It is unclear whether light physical activity is beneficially associated with insulin resistance, similar to moderate and/or vigorous physical activity. This cross-sectional study was performed to determine the relationship between the amount of light physical activity, as determined with a triaxial accelerometer, and insulin resistance.;METHODS:A total of 807 healthy men and women participated in this study. Physical activity was measured using a triaxial accelerometer worn for 28 days and summarized as light intensity (1.1-2.9 METs) or moderate to vigorous intensity (≥ 3.0 METs). Insulin resistance was evaluated by HOMA_R (FPG [mg/dL] × IRI [μU/mL]/405).;RESULTS:The daily time spent in light physical activity was inversely associated with HOMA_R (r = -0.173, P < 0.05). After adjustment for confounders, the association between light physical activity and HOMA_R remained statistically significant (β = -0.119, P < .05). Light physical activity remained significantly associated with HOMA_R following further adjustment for moderate to vigorous intensity activity (β = -0.125, P < .05). Similar results were observed when light physical activity was modeled as quartiles, especially in elderly women.;CONCLUSIONS:These cross-sectional data suggest that light-intensity physical activity is beneficially associated with insulin resistance in elderly Japanese women.

Home-based active video games to promote weight loss during the postpartum period.

Tripette Julien;Murakami Haruka;Gando Yuko;Kawakami Ryoko;Sasaki Azusa;Hanawa Satoshi;Hirosako Aiko;Miyachi Motohiko

Med Sci Sports Exerc査読有り46(3)p.472 - 4782014年03月-

PubMedDOIWoS

詳細

ISSN:1530-0315

概要:PURPOSE:Weight retention during the postpartum period is critical for the later development of obesity in women. Traditional physical activity is frequently discontinued because of incompatibility with mothers' agenda (i.e., baby care). In the present study, active video games (AVG) are proposed for postpartum women to improve their body composition.;METHODS:Thirty-four postpartum women (body mass index = 24.5 ± 3.4 kg·m) were randomized to an AVG group or a control group. Subjects assigned to the AVG group were given a Wii Nintendo console with the game Wii Fit Plus for 40 d. The two groups were tested for weight, body mass index, body fat mass, waist and hip circumferences, and other anthropometric parameters. Physical fitness, energy expenditure, energy intake, and adverse events were also investigated.;RESULTS:The AVG group lost more weight than the control group (-2.2 ± 0.9 vs. -0.5 ± 0.7 kg, P < 0.001). They also exhibited more important reductions of BMI, waist and hip circumferences, and body fat (P < 0.05). During the 40-d period, subjects expended an estimated 4682 ± 2874 kcal just by playing AVG. Daily energy intake was reduced by 206 ± 559 kcal. There were significant positive correlations between playing frequency, total playing time, total energy expenditure during the 40-d period, and decrease in daily energy intake respectively, and weight loss (P < 0.05). Playing time data suggested no conflict with baby care activities.;CONCLUSIONS:AVGs could represent an interesting spare physical activity for postpartum women. In the present study, these games promoted physical activity, induced a reduction of energy intake, and subsequently minimized weight retention.

Reference values for cardiorespiratory fitness and incidence of type 2 diabetes.

Kawakami Ryoko;Sawada Susumu S;Matsushita Munehiro;Okamoto Takashi;Tsukamoto Koji;Higuchi Mitsuru;Miyachi Motohiko

J Epidemiol査読有り24(1)p.25 - 302014年-

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詳細

ISSN:1349-9092

概要:BACKGROUND:In "Physical Activity Reference for Health Promotion 2013" the Japan Ministry of Health, Labour and Welfare publication gives reference values for cardiorespiratory fitness (CRF) required for good health. We examined the associations between the CRF reference values and incidence of type 2 diabetes.;METHODS:This prospective cohort study enrolled 4633 nondiabetic Japanese men aged 20 to 39 years at baseline. CRF was measured using the cycle ergometer test, and maximal oxygen uptake was estimated. On the basis of the CRF reference value, participants were classified into 2 groups: those with values less than the reference value (under-RV) and those with values equal to or greater than reference value (over-RV). Hazard ratios (HRs) and 95% CIs for incident type 2 diabetes were estimated using a Cox proportional hazards model.;RESULTS:A total of 266 participants developed type 2 diabetes during the 14 years of follow-up. As compared with the under-RV group, the over-RV group had a significantly lower multivariable-adjusted HR for type 2 diabetes (HR 0.67; 95% CI, 0.51-0.89). In receiver operating characteristic analysis, the optimal CRF cut-off value for predicting incident type 2 diabetes was 10.8 metabolic equivalents (sensitivity, 0.64; specificity, 0.64), which was close to the CRF reference value of 11.0 metabolic equivalents.;CONCLUSIONS:The reference CRF value appears to be reasonably valid for prevention of type 2 diabetes, especially among Japanese men younger than 40 years. Development of type 2 diabetes can be prevented by maintaining a CRF level above the reference value.

身体活動と運動のそれぞれの意義

村上晴香, 川上諒子, 宮地元彦

体育の科学63(12)p.950 - 9552013年12月-

わが国の疫学的知見からみた身体活動基準

澤田亨, 村上晴香, 川上諒子, 宮地元彦

体育の科学63(12)p.944 - 9492013年12月-

全身持久力および飲酒習慣が全がん死亡率に与える影響:日本人男性を対象としたコホート研究

松下宗洋, 宮地元彦, 川上諒子, 岡本隆史, 塚本浩二, 中田由夫, 荒尾孝, 澤田亨

体力科学査読有り62(5)p.375 - 3812013年10月-

DOI

活動量計とTwitterを併用した生活介入が身体活動量に与える影響−無作為割り付け介入試験

西脇雅人, 中嶋名菜, 池上由美, 川上諒子, 黒部一道, 松本直幸

体力科学査読有り62(4)p.293 - 3022013年08月-

DOI

健康づくりのための体力の基準値の考え方と活用

澤田亨, 村上晴香, 川上諒子, 宮地元彦

臨床栄養123(1)p.36 - 432013年07月-

高齢者における目標値の設定法と考え方

村上晴香, 川上諒子, 田中憲子, 宮地元彦

臨床栄養123(1)p.31 - 352013年07月-

健康づくりのための身体活動基準2013とアクティブガイドの策定手順と概要

宮地元彦, 村上晴香, 川上諒子, 田中憲子, 田中茂穂, 高田和子, 宮武伸行, 小熊祐子, 澤田亨, 種田行男, 田畑泉

臨床栄養123(1)p.24 - 302013年07月-

健康づくりのための身体活動基準・指針2013の概要

宮地元彦, 村上晴香, 澤田亨, 川上諒子, 田中憲子, 田中茂穂, 高田和子, 宮武伸行, 小熊裕子, 種田行男, 田畑泉

日本栄養士会雑誌56(3)p.4 - 132013年03月-

Higher cardiorespiratory fitness attenuates arterial stiffening associated with the Ala54Thr polymorphism in FABP2

Fujie, Shumpei;Iemitsu, Motoyuki;Murakami, Haruka;Sanada, Kiyoshi;Kawano, Hiroshi;Gando, Yuko;Kawakami, Ryoko;Miyachi, Motohiko

PHYSIOLOGICAL GENOMICS査読有り45(6)p.237 - 2422013年-2013年03月 

PubMedDOIWoS

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ISSN:1094-8341

Adverse effects of coexistence of sarcopenia and metabolic syndrome in Japanese women

Sanada K, Iemitsu M, Murakami H, Gando Y, Kawano H, Kawakami R, Tabata I, Miyachi M

Eur J Clin Nutr査読有り66(10)p.1093 - 10982012年10月-

PubMedDOI

健康日本21(第二次)・身体活動基準2013およびアクティブガイド

澤田亨, 村上晴香, 川上諒子, 宮地元彦

日本食生活学会誌24(3)p.139 - 1422012年09月-

健康づくりのための運動基準2006の改定の手順と方向性

宮地元彦, 村上晴香, 川上諒子, 田中憲子, 田中茂穂, 高田和子, 宮武伸行, 小熊裕子, 澤田亨, 種田行男, 田畑泉

体育の科学62(9)p.644 - 6502012年09月-

健康づくりのための運動基準2006における身体活動量の基準値週23メッツ・時と 1 日あたりの歩数との関連

村上晴香, 川上諒子, 大森由実, 宮武伸行, 森田明美, 宮地元彦

体力科学査読有り61(2)p.183 - 1912012年04月-

DOI

Associations among objectively measured physical activity, fasting plasma homocysteine concentration, and MTHFR C677T genotype

Murakami H, Iemitsu M, Sanada K, Gando Y, Ohmori Y, Kawakami R, Sasaki S, Tabata I, Miyachi M

Eur J Appl Physiol査読有り111(12)p.2997 - 30052011年12月-

PubMedDOI

特集 予備群と特定健診 標準的な質問票の妥当性は?

川上諒子, 宮地元彦

肥満と糖尿病10(4)p.594 - 5952011年07月-

Vascular adaptations to hypobaric hypoxic training in postmenopausal women

Nishiwaki M, Kawakami R, Saito K, Tamaki H, Takekura H, Ogita F

J Physiol Sci査読有り61(2)p.83 - 912011年03月-

PubMedDOI

Attenuated Age-Related Carotid Arterial Remodeling in Adults with a High Level of Cardiorespiratory Fitness

Gando, Yuko;Yamamoto, Kenta;Kawano, Hiroshi;Murakami, Haruka;Ohmori, Yumi;Kawakami, Ryoko;Sanada, Kiyoshi;Higuchi, Mitsuru;Tabata, Izumi;Miyachi, Motohiko

J Atheroscler Thromb査読有り18(3)p.248 - 2542011年-

PubMedDOIWoS

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ISSN:1340-3478

特定健診・保健指導の標準的な質問票を用いた身体活動評価の妥当性

川上諒子, 宮地元彦

日本公衆衛生雑誌査読有り57(10)p.891 - 8992010年10月-

PubMed

Longer Time Spent in Light Physical Activity Is Associated With Reduced Arterial Stiffness in Older Adults

Gando, Yuko;Yamamoto, Kenta;Murakami, Haruka;Ohmori, Yumi;Kawakami, Ryoko;Sanada, Kiyoshi;Higuchi, Mitsuru;Tabata, Izumi;Miyachi, Motohiko

Hypertension査読有り56(3)p.540 - 5462010年09月-

PubMedDOIWoS

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ISSN:0194-911X

閉経後女性の動脈スティフネスと最大下運動時における血圧応答の関係

西脇雅人, 川上諒子, 齊藤和人, 田巻弘之, 竹倉宏明, 福岡義之, 荻田太

トレーニング科学査読有り21(3)p.297 - 3092009年10月-

書籍等出版物

トレーニングのための生理学的知識

著者:Zsolt Radák, 監訳:樋口満(共訳)

市村出版2018年 10月-

LINK

詳細

担当ページ数:120-132ISBN:9784902109504

外部研究資金

科学研究費採択状況

研究種別:特別研究員奨励費(DC2)

質問紙を用いたサルコペニアのスクリーニング・簡易評価法の開発

2013年04月-2015年03月

研究分野:応用健康科学

配分額:¥2000000

研究種別:スタート支援

身体活動およびその他の生活習慣要因とサルコペニアの関連構造を解明する

2015年08月-2017年03月

配分額:¥2990000

研究種別:若手研究

下腿周囲径計測によるサルコペニア簡易評価の臨床的意義と確立への展開

2018年04月-2021年03月

配分額:¥4030000

研究資金の受入れ状況

提供機関:財団法人 石本記念デサントスポーツ科学振興財団実施形態:研究助成金

サルコペニアの簡易評価法としての椅子片脚立ち上がりテストの妥当性検証研究2015年-

代表

提供機関:公益財団法人 上原記念生命科学財団実施形態:研究助成金

各種体⼒要素と難聴発症に関する予防疫学研究2020年02月-2021年04月

代表

学内研究制度

特定課題研究

サルコペニア予防のために必要な身体活動の量およびその強度に関する研究

2015年度

研究成果概要:本研究では、身体活動量とサルコペニアとの関連について横断的に検討することを目的とした。40歳から85歳の中高齢女性509人を対象とした。三次元加速度計を用いて客観的に身体活動量を評価した。また、DXA法を用いて評価した骨格筋指数を...本研究では、身体活動量とサルコペニアとの関連について横断的に検討することを目的とした。40歳から85歳の中高齢女性509人を対象とした。三次元加速度計を用いて客観的に身体活動量を評価した。また、DXA法を用いて評価した骨格筋指数をもとに、サルコペニアを判定した。中強度以上の身体活動量の三分位によるサルコペニアのオッズ比を求めた結果、身体活動量が最も少ない第1三分位に対する各分位の調整オッズ比(95%信頼区間)は、第2三分位で0.83(0.54-1.29)、第3三分位で0.53(0.34-0.83)となり、有意な負の量反応関係が認められた(P=0.006)。以上より、中強度以上の身体活動量が多い女性ではサルコペニア該当者が少ない可能性が示唆された。

筋量の簡易評価指標としての下腿周囲径と体力との関連

2017年度

研究成果概要:本研究では、筋量の簡易評価指標としての下腿周囲径と体力との関連について横断的に検討することを目的とした。対象者は40歳以上の中高齢男女898人であった。立位時の下腿最大周囲径、握力および脚伸展パワーの測定を行った。下腿周囲径は、握...本研究では、筋量の簡易評価指標としての下腿周囲径と体力との関連について横断的に検討することを目的とした。対象者は40歳以上の中高齢男女898人であった。立位時の下腿最大周囲径、握力および脚伸展パワーの測定を行った。下腿周囲径は、握力(r=0.58)および脚伸展パワー(r=0.59)との間に中程度の正の相関関係が認められた。ROC曲線による解析の結果、低筋量者(握力:男性<30kg、女性<20kg)を予測するための下腿周囲径のカットオフ値は男性27.5cm(感度67%、特異度64%)、女性25.3cm(感度60%、特異度62%)であった。以上より、精度はそれほど高くはないものの、下腿周囲径計測によって低筋力の簡易評価が可能であることが示唆された。

下腿周囲径計測による全身筋量評価に対する上肢と下肢の筋量比の影響

2019年度

研究成果概要:本研究では、下腿周囲径計測による全身筋量評価に対する上肢と下肢の筋量比の影響を検証することを目的とした。対象者は40歳以上の中高齢男女1248人であった。立位時の下腿最大周囲径とDXAによる身体組成の測定を行った。上肢と下肢の筋量...本研究では、下腿周囲径計測による全身筋量評価に対する上肢と下肢の筋量比の影響を検証することを目的とした。対象者は40歳以上の中高齢男女1248人であった。立位時の下腿最大周囲径とDXAによる身体組成の測定を行った。上肢と下肢の筋量の間には強い正の相関関係が認められた(男性r=0.83、女性r=0.81)。低筋量に対する下腿周囲径のROC曲線のアンダーカーブ面積は、上肢筋量が占める割合が多い群(男性0.85、女性0.81)よりも、少ない群(男性0.91、女性0.86)でわずかに高値となったが、いずれの群も高いアンダーカーブ面積であった。以上より、上肢筋量が占める割合が多い者ではわずかに精度が下がるものの、下腿周囲径計測によって低筋量の簡易評価が可能であることが示唆された。

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2017年04月- 2018年03月武蔵野大学非常勤講師